Fertility and ageing – can raising NAD+ levels help?
Recent research suggests that improving NAD+ levels leads to increased measures of fertility in ageing mice.
One of the earliest signals of age-related decline is seen in the female reproductive system.
With increased age, the number and quality of oocytes (immature eggs) decreases. It is suspected that the decline in the number of mitochondria may play a role in reduced fertility due to age.
Two new studies in mice now suggest that increasing NAD+ levels improves mitochondrial function, and therefore fertility, in ageing ovaries.
Further research is needed to determine whether the fertility boosting effects of NAD+ seen in mice can be replicated in humans.